Membrane-bound immunoglobulin is associated with a heterodimer of mb-1 (CD79a) and B29 (CD79b) proteins. The antibody JCB117 is superior to HM57 in its specificity for CD79a; the latter shows cross-reactivity with smooth muscle.

Antibodies are effective on paraffin-embedded tissue1.

Immunohistochemical expression

Diagnostic utility



1 Leong A S-Y, Cooper K and Leong FJ W-M. Manual of diagnostic antibodies for immunohistology. 2nd edition, 2003

2 Torlakovic, E., G. Torlakovic, et al. (2002). “The value of anti-pax-5 immunostaining in routinely fixed and paraffin- embedded sections: a novel pan pre-B and B-cell marker.” Am J Surg Pathol 26(10): 1343-50.

3 Arber DA, Jenkins KA,Slovak ML CD79 alpha expression in acute myeloid leukemia. High frequency of expression in acute promyelocytic leukemia. Am J Pathol 1996; 149:1105-10



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