Granulosa cell tumour of testis, juvenile type
Epidemiology
Usually occurs in infants less than six months old.
Clinical features
Hormonal manifestations are rare.
Histopathology
Solid aggregates of tumour cells with large follicle-like cystic spaces containing basophilic mucoid fluid. Nuclear grooves and Call-Exner bodies are usually not seen.
Immunohistochemistry
Differential diagnosis
Prognosis
Malignant behaviour has not been reported.
References
1Shanks JH, Iczkowski KA. Non-germ cell tumours of the testis. Current Diagnostic Pathology 2002;8:83-93.
2Kommoss, F., Oliva, E., Bittinger, F., Kirkpatrick, C. J., Amin, M. B., Bhan, A. K., Young, R. H., Scully, R. E. Inhibin-alpha CD99, HEA125, PLAP, and chromogranin immunoreactivity in testicular neoplasms and the androgen insensitivity syndrome. Hum Pathol 2000;31:1055-61.
3Perez-Atayde, A. R., Joste, N., Mulhern, H. Juvenile granulosa cell tumor of the infantile testis. Evidence of a dual epithelial-smooth muscle differentiation. Am J Surg Pathol 1996;20:72-9.
This page last revised 2.12.2002.
©SMUHT/PW Bishop