MCM2 is a member of the prereplicative complex. It is present replicating throughout the cell cycle but is lost on differentiation or quiescence.

Immunohistochemical expression


Diagnostic utility

Diagnosis of malignant mesothelioma in pleural biopsies


1 Sington JD, Morris LS, Nicholson AG, et al. Assessment of cell cycle state may facilitate the histopathological diagnosis of malignant mesothelioma. Histopathology 2003; 42:498-502

This page last revised 24.1.2007.

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