Mature B cell neoplasms

Epidemiology

Mature B cell neoplasms account for 4% of all cancers and 90% of all lymphomas.

Classification is based on all available evidence to define disease entities. Mature B cell lymphomas are listed according to their major clinical presentation:

predominantly disseminated lymphomas / leukaemias

chronic lymphocytic leukaemia / small cell lymphoma

B-cell prolymphocytic leukaemia

lymphoplasmacytic lymphoma / Waldenstrom's macroglobulinaemia

splenic marginal zone lymphoma

hairy cell leukaemia

plasma cell myeloma

 

primary extranodal lymphomas
MALT-lymphoma

 

predominantly nodal lymphomas
nodal marginal zone lymphoma
follicular lymphoma
mantle cell lymphoma
 

 

either nodal or extranodal
diffuse large B cell lymphoma
subtype: mediastinal (thymic) large B cell lymphoma

 

others
primary effusion lymphoma
Burkitt lymphoma / leukaemia
lymphomatoid granulomatosis

 

Relative frequencies

References

World Health Organization Classification of Tumours, Tumours of the haematopoietic and lymphoid tissues, IARC Press 2001.

 

This page last revised 17.12.2002.

©SMUHT/PW Bishop