Low-affinity Nerve growth factor receptor (p75NGFR)

This 75-kd surface receptor glycoprotein is found on non-myelin-forming Schwann cells, perineural cells and nerve fibres.

Immunohistochemical expression

• neurofibroma

• schwannoma

• intraneural perineuroma

• Myxoid neurothekeoma

• granular cell tumour

• Follicular dendritic cell tumour/sarcoma

References

WB Laskin et al. The "Neurothekeoma": immunohistochemical analysis distinguishes the true nerve sheath myxoma from its mimics. Hum Pathol 2000;31:1230-1241.

©SMUHT/PW Bishop