A thymic carcinoma composed of large atypical epithelial cells, lacking overt keratinisation. This is not a separate category in the current WHO classification but is included with keratinising squamous carcinoma.
Similar to thymic squamous cell carcinoma but lacks overt keratinisation. Lobulation is absent or less well developed than in thymic squamous cell carcinoma.
Cytokeratin |
4/42 |
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4/42 |
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4/52 |
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almost always positive, 3/52 |
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positive in about 50% of cases, 3/52 |
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positive in about 50% of cases, 3/52 |
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3/52 |
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Type B3 thymoma: negative for CD5, chromogranin and synaptophysin.
J Rosai et al. Histological typing of tumours of the thymus. WHO International histological classification of tumours. Springer-Verlag, second edition, 1999.
This page last revised 6.1.2006.
©SMUHT/PW Bishop