|
"positive": score > 3 |
Endometrial |
Endocervical |
Conclusion |
||||||
|
endometrioid |
mucinous |
endometrioid |
mucinous |
||||||
|
mean (range) |
positive |
mean (range) |
positive |
mean (range) |
positive |
mean (range) |
positive |
||
|
5.7 (0-12) |
20/27 |
4.2 (0-12) |
9/17 |
1.6 (0-6) |
1/5 |
0 |
1/10 |
score relates mainly to site |
|
|
7.6 (0-12) |
24/27 |
2.8 (0-6) |
7/17 |
6.0 (0-12) |
3/5 |
0.1 (0-1) |
1/10 |
score relates mainly to type |
|
|
CK4 |
9.2 (0-12) |
|
4.4 (0-12) |
|
10.6 (8-12) |
|
8.5 (6-12) |
|
not useful |
|
6.4 (0-12) |
|
3.4 (0-8) |
|
8.4 (6-12) |
|
5.5 (0-12) |
|
not useful |
|
|
0.7 ( 0-12) |
|
0 |
|
0.4 (0-2) |
|
0.5 (0-1) |
|
almost always negative |
|
|
0.4 (0-6) |
2/27 |
0.9 (0-6) |
1/17 |
1.2 (0-6) |
1/5 |
5.1 (1-12) |
5/10 |
scores highly only in some mucinous endocervical carcinomas |
|
|
6.9 ( 0-12) |
24/27 |
1.9 ( 0-12) |
3/17 |
4.4 (0-12) |
2/5 |
0 |
0/10 |
scores highly only in endometrial endometrioid carcinomas |
|
Immunoreactivity was scored as for the German Immunohistochemical Scoring System:
percentage of positive cells (PPS); 0=negative, 1 = up to 10% positive, 2 = 11 to 50% positive, 3 = 51 to 80% positive, 4 = more than 800% positive
Staining intensity (SI); 0 = negative, 1 = weak, 2 = moderate, 3 = strong.
Score = PSS x SI (maximum score = 12). A score of 3 or less is essentially "negative".
References
This page last revised 4.5.2004.
©SMUHT/PW Bishop