Human Kidney Injury Molecule-1 (hKIM-1), T cell immunoglobulin domain and mucin domain protein (TIM-1), Hepatitis A virus cellular receptor 1 (HAVCR1)

Renal tumours

Conventional renal cell carcinoma

54/73(staining was diffuse in 20 of these cases)1, 24/35(17 cases showed staining of more than 50% of tumour cells)2

Papillary renal cell carcinoma

28/30(staining was diffuse in 14 of these cases)1, 2/32

Chromophobe renal cell carcinoma

0/541, 0/22

Oncocytoma

4/411

Metastatic renal cell carcinoma

35/45(9/12 to lung, 7/10 to bone, 6/7 to lymph nodes, 4/6 to brain, 2/2 to thyroid, 2/2 to skin, 2/3 to soft tissues, 1/2 to testis)1

Sarcomatoid renal cell carcinoma

2/21

Non-renal tumours

Clear cell carcinoma of the ovary

15/161

Serous carcinoma of the ovary

0/15

Endometrioid carcinoma of the ovary

0/2

Clear cell carcinoma of the uterus

6/18(the 6 positive cases showed staining of less than 10% of tumour cells)1

Endometrioid carcinoma of the uterus

0/13

Serous carcinoma of the uterus

0/2

Adenocarcinoma of the colon

5/40(all 5 positive cases were well differentiated: staining was only focal in 4 of these cases)1

Breast ductal carcinoma

0/17

Breast lobular carcinoma

0/8

Pancreatic adenocarcinoma

0/13

Hepatocellular carcinoma

0/13

Lung adenocarcinoma

0/10

Prostatic adenocarcinoma

0/15

Renal pelvic urothelial carcinoma

0/10

Thyroid papillary carcinoma

0/10

Mesothelioma

0/6

Neuroendocrine carcinoma, site unspecified

0/10

Total

26/2211, 2/484(cases included tumours of CNS, lymphomas, melanomas, ovarian, breast, colon, lung and prostatic carcinomas: the two positive cases were hepatocellular carcinomas)2