Pancreatic tumours: differential diagnosis

 

endocrine tumours

solid pseudopapillary tumour

acinar cell tumour

pancreatoblastoma

poorly differentiated ductal carcinoma

clear cell carcinoma

oncocytic carcinoma

a-1-antitrypsin

 

focally intensely positive

         

cytokeratin

positive

weak or negative

         

vimentin

 

diffusely positive

         

NSE

positive

diffusely positive

         

other neuroendocrine markers

positive

negative

scattered cells may be positive

scattered cells may be positive

     

pancreatic enzymes

   

positive

positive

     

AFP

     

some

     

CEA

       

positive

positive

positive

Ca19.9

       

positive

positive

positive

               

References

Diagnostic histopathology of tumors. Edited by CDM Fletcher. 2nd edition. Churchill Livingstone. Page 1093.

This page last revised 1.6.2001.

©SMUHT/PW Bishop