TTF-1
in extra-pulmonary adenocarcinoma (excluding thyroid neoplasms)
|
Breast |
0/141 (0/965, 0/1815,
0/5 (signet
ring cell carcinomas)19,
0/7
(metastases to brain)23,
0/534, 0/10(using
monoclonal 8G7G3/1)6), 0/13(using
clone 8G7G3/1)7, 0/8(cell
blocks from cases with metastatic adenocarcinoma to serous cavities,
using clone 8G7G3/1)9, 0/51(using
a polyclonal antibody)1, 0/2(lung
metastasis, using clone 8G7G3/1)8,
0/25(using
clone 8G7G3/1)35 |
|
Salivary gland |
0/3
(metastases to brain)23 |
|
Oesophagus |
0/315 |
|
Stomach |
1/98 (1/661, 0/315,
0/519, 0/2431),
0/2(using
clone 8G7G3/1)7, 0/9(cell
blocks from cases with metastatic adenocarcinoma to serous cavities,
using clone 8G7G3/1)9 |
|
Colon |
0/230 (0/18
(primary tumours, using polyclonal antibody)1,
0/21 (primary
tumours, using clone8G7G3/1)2, 0/30(primary
tumours, using clone8G7G3/1)4 , 0/20(primary
tumours, using clone 8G7G3/1)6,
0/26(primary
tumours, using clone 8G7G3/1)7,
0/3(lung
metastasis, using clone 8G7G3/1)8,
0/8(cell
blocks from cases of metastatic carcinoma to serous cavities, using
clone 8G7G3/1)9, 0/6(lung
metastasis, using clone 8G7G3/1)10,
0/5(lung
metastasis, using clone 8G7G3/1)11,
0/26(lung
metastasis, using clone 8G7G3/1)12,
0/519, 0/1(metastases
to brain)23,
0/3531, 0/1634), 0/10(using
clone 8G7G3/1)35 |
|
Liver |
0/22(using
monoclonal 8G7G3/1)6, 0/2(lung
metastasis, using clone 8G7G3/1)8 |
|
Gallblader |
0/115 |
|
Pancreas |
0/9 (0/215,
0/731) |
|
Kidney |
0/41 (0/185, 0/14
(metastases to brain)23,
0/934), 0/7(using
clone 8G7G3/1)7, 0/8(using
a polyclonal antibody)1, 0/2(lung
metastasis, using clone 8G7G3/1)8,
0/10(using
clone 8G7G3/1)35 |
|
Ovary |
16/116 (0/305, 1/16
(few very weakly reactive cells)15,
0/1531, 15/53
(endometrioid: 3/8, serous: 6/25; strong in one case, clear cell: 4/10;
strong in two cases, mucinous: 2/10; strong in one case)33,
0/234), 0/15(cell
blocks from cases with metastatic adenocarcinoma to serous cavities,
using clone 8G7G3/1)9, 0/4(lung
metastasis, using clone 8G7G3/1)8,
0/30(using
clone 8G7G3/1)35 |
|
Endometrium |
1/40 (1/81, 0/415,
0/2531, 0/334), 0/1(using
monoclonal 8G7G3/1)6, 0/6(lung
metastasis, using clone 8G7G3/1)8 |
|
Prostate |
0/21 (0/195, 0/215),
0/9(using a
polyclonal antibody)1, 0/1(lung
metastasis, using clone 8G7G3/1)8,
0/10(using
clone 8G7G3/1)35 |
|
Total |
18/534 (2/2865,
1/4915,
0/1519,
0/2523,
0/10631, 15/5333) |
15using
cell blocks from FNAs
I have seen one focally positive colorectal
metastasis to lung., unpublished case.
References
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A, Dingle S, Bejarano PA, et al. Monoclonal antibody to thyroid
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NG. Value of thyroid transcription factor-1 immunostaining in
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O,Dietel M Thyroid transcription factor-1 is the superior
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This page last revised30.7.2004.
©SMUHT/PW Bishop