Acid phosphatase (tartrate resistant)

This enzyme may now be detected in paraffin embedded tissue using a monoclonal antibody.

Immunohistochemical expression

• Almost all cases of hairy cell leukaemia

• Some marginal zone lymphomas

• Mast cell proliferations: systemic mastocytosis

Diagnostic utility

• Hairy cell leukaemia

References

©SMUHT/PW Bishop