Adrenal tumours

 

adrenal cortical adenoma and carcinoma

phaeochromocytoma

cytokeratin

may be positive after protease digestion1

negative1

EMA

negative1

negative1

vimentin

positive1

 

synaptophysin

variable1

positive1,2

chromogranin

negative1

positive1,2

NSE

variable1

positive1

tyrosine hydrolase

 

positive2

neurofilament

variable1

 negative2

D11

nuclear positivity1

 

S-100

 

sustentacular cells positive1,2

     

 

References

1Diagnostic histopathology of tumors. Edited by CDM Fletcher. 2nd edition. Churchill Livingstone. Pages 1066-1071.

2Pello, J. M., Guate, J. L., Naves, F. J., Escaf, S., Vega, J. A. Neurotrophins and neurotrophin receptors in some neural crest-derived tumours (ganglioneuroma, phaeochromocytoma and paraganglioma) Histopathology 1999;34:216-225

This page last revised 13.6.2001.