CD11

The available antisera work only on cryostat sections1.

Immunohistochemical expression

• CD11a, leukocyte function-associated protein (LFA-1)

  • B cells

  • T cells

  • NK cells

  • monocytes

  • granulocytes

  • megakaryocytes and activated platelets

• CD11b, the C3bi receptor

  • granulocytes

  • monocytes

  • some histiocytes

• CD11c

  • monocytes

  • tissue macrophages

  • granulocytes

  • some suppressor/cytotoxic T cells

  • NK cells

  • some B cells

  • true histiocytic neoplasms

  • hairy cell leukaemia

  • some monocytoid B cell lymphoma

Diagnostic utility

References

1Leong A S-Y, Cooper K and Leong FJ W-M. Manual of diagnostic antibodies for immunohistology. 2nd edition, 2003

©SMUHT/PW Bishop