MAC 387 (macrophage marker)

Immunohistochemical expression

macrophages
haemophagocytic syndrome
Rosai-Dorfman disease
Langerhans' cell histiocytosis
true histiocytic lymphomas
some anaplastic large cell lymphomas
squamous cell carcinomas of skin, bronchus, bladder and oral cavity

	Malignant pleural epithelioid mesothelioma	0/211
	Malignant peritoneal epithelioid mesothelioma	0/211
	Peripheral pulmonary adenocarcinoma involving pleura	0/231
	Serous surface papillary adenocarcinoma of peritoneum	0/101
	Breast carcinoma metastatic to pleura	0/101

Diagnostic utility

MAC 387 is a less specific macrophage marker than is KP1

References

1 Wick MR, Mills SE,Swanson PE Expression of "myelomonocytic" antigens in mesotheliomas and adenocarcinomas involving the serosal surfaces. Am J Clin Pathol 1990; 94:18-26

This page last revised 19.8.2005.

©SMUHT/PW Bishop