BCA-225

Immunohistochemical expression

This glycoprotein was originally identified in breast carcinomas.  It is commonly present in carcinomas of breast, kidney, ovary, lung and other adenocarcinomas.

Diagnostic utility

References

Mesa-Tejada R, Palakodety RB, Leon JA, et al. Immunocytochemical distribution of a breast carcinoma associated glycoprotein identified by monoclonal antibodies. Am J Pathol 1988; 130:305-14

Loy TS, Chapman RK, Diaz-Arias AA, et al. Distribution of BCA-225 in adenocarcinomas. An immunohistochemical study of 446 cases. Am J Clin Pathol 1991; 96:326-9

Ma CK, Zarbo RJ, Frierson HF, Jr., et al. Comparative immunohistochemical study of primary and metastatic carcinomas of the liver. Am J Clin Pathol 1993; 99:551-7

©SMUHT/PW Bishop