CD25

This is the interleukin-2 receptor. Interleukin-2 conjugated to diptheria toxin has been used in the treatment of mycosis fungoides1; this is predicated on demonstration of expression of CD25 by the neoplasm.

Immunohistochemical expression

Diagnostic utility

References

1Liu V., McKee PH. Cutaneous T-cell lymphoproliferative disorders; approach for the surgical pathologist: recent advances and clarification of confused issues. Advances in Anatomic Pathology 2002;9:79-100..

©SMUHT/PW Bishop