CD5

CD5 is a 67 kDa glycoprotein.

Antibody clone NCL-CD5-4C7 is effective on paraffin-embedded tissue3. The Leu1 antibody will also stain paraffin-embedded tisue after antigen retrieval and tyramine-enhanced detection.

Immunohistochemical expression

Diagnostic utility

References

1 S Pomplun. Immunohistochemical markers in the differentiation of thymic and pulmonary neoplasms. Abstract 158, Pathological Society of Great Britain and Ireland January 2001.

2 Bakels, V., van Oostveen, J.W., van der Putte, S.C., Meijer, C.J. and Willemze, R. Immunophenotyping and gene rearrangement analysis provide additional criteria to differentiate between cutaneous T-cell lymphomas and pseudo- T-cell lymphomas. Am J Pathol 1997;150:1941-9.

3 Leong A S-Y, Cooper K and Leong FJ W-M. Manual of diagnostic antibodies for immunohistology. 2nd edition, 2003

4 Pan, C. C., P. C. Chen, et al. (2003). "Expression of calretinin and other mesothelioma-related markers in thymic carcinoma and thymoma." Hum Pathol 34(11): 1155-62.

5 Kitamura A, Yamashita Y, Hasegawa Y, et al. Primary lymphoma arising in the nasal cavity among Japanese. Histopathology 2005; 47:523-32

 

 

©SMUHT/PW Bishop