Laminin

This is an important component of basement membranes. It acts as a bridge between collagen type IV in the basement membrane and the glycosaminoglycans of the surrounding matrix. In soft tissues, complete basement membranes form around endothelial, smooth muscle and Schwann cells: antibodies against laminin and collagen IV are useful for the identification of these lineages.

References

¹Diagnostic Immunohistochemistry edited by Professor D. J. Dabbs, page 70

This page last revised 21.12.2001.

©SMUHT/PW Bishop