Parachordoma (chordoma periphericum, chordoid sarcoma)

Epidemiology

This is a rare soft tissue tumour. Its characteristics are not fully established. There are about 20 published cases.

Histopathology

Shows features of (a) extraskeletal myxoid chondrosarcoma, (b) chordoma and (c) chondroid syringoma.

Immunohistochemistry

Focally positive for cytokeratins 19 and 8 and for EMA.

Focally positive for S-100, mainly in areas of cartilaginous appearance.

Negative for SMA and GFAP

References

Karabela-Bouropoulou, V., Skourtas, C., Liapi-Avgeri, G., Mahaira, H..  A case report of a very rare soft tissue tumor.  Pathol Res Pract 1996;1992:972-8.

Adv Anat Pathol 1997;4:256.

©SMUHT/PW Bishop