NESP-55

NESP-55 is a member of the chromogranin family restricted to adrenal chromaffin cells and pancreatic islet cells.

Immunohistochemical expression

• Phaeochromocytoma

• Pancreatic endocrine tumours

Diagnostic utility

• Differentiation of pancreatic endocrine tumours from gastrointestinal and pulmonary carcinoids.

References

1 Srivastava A,Hornick JL. mmunohistochemical staining for CDX-2, PDX-1, NESP-55, and TTF-1 can help distinguish gastrointestinal carcinoid tumors from pancreatic endocrine and pulmonary carcinoid tumors. Am J Surg Pathol 2009; 33:626-32

This page last revised 18.4.2009.

©SMUHT/PW Bishop