Neuroendocrine markers - comparison

 

CD56

CD57

chromogranin

synaptophysin

NSE

PGP 9.5

 

lung

adenocarcinoma

1/381

4/381

0/381

1/381

13/381

12/381

squamous carcinoma

4/521

0/521

0/521

1/521

25/521

18/521

small cell carcinoma

65/661

4/661

7/661

27/661

62/661

33/661

large cell carcinoma- neuroendocrine

2/21

0/21

2/21

2/21

2/21

2/21

non-endocrine large cell carcinoma

2/31

0/31

0/31

0/31

1/31

0/31

extrapulmonary small cell carcinoma

4/41

0/41

1/41

2/41

4/41

1/41

renal cell carcinoma

6/301

4/291

0/291

1/291

27/291

12/291

ovarian carcinoma

7/281

1/121

0/121

0/121

10/121

3/121

endometrial carcinoma

2/101

0/101

0/101

0/101

7/101

2/101

cervical squamous carcinoma

0/151

0/151

0/151

0/151

 

 

breast

invasive ductal

0/301

0/171

0/171

0/171

3/171

0/171

invasive lobular

0/61

0/31

0/31

0/31

0/31

0/31

gastric

intestinal type

0/81

0/21

0/21

0/21

0/21

0/21

diffuse type

0/111

1/111

0/111

0/111

1/111

1/111

prostatic carcinoma

0/131

13/131

0/131

0/131

1/131

1/131

urothelial carcinoma

0/171

1/171

0/171

0/171

4/171

1/171

hepatic carcinoma

0/111

         

colonic carcinoma

0/121

0/121

0/121

0/12

0/121

1/121

pancreatic carcinoma

0/221

0/201

0/201

0/201

10/201

2/201

squamous carcinoma head & neck

0/381

0/201

0/201

0/201

5/201

4/201

 

References

1Kaufmann, O., Georgi, T. and Dietel, M. Utility of 123C3 monoclonal antibody against CD56 (NCAM) for the diagnosis of small cell carcinomas on paraffin sections. Hum Pathol 1997;28:1373-8.

 

This page last revised 23.2.2003.

©SMUHT/PW Bishop