CD57 (Leu7)

This myelin-associated glycoprotein is present on Schwann cells.

Antibodies are effective on paraffin-embedded tissue3. Leu7 is the prototypic anti-CD57, also designated HNK-1.

Immunohistochemical expression

Diagnostic utility


1Kraus, M. D., Haley, J. Lymphocyte predominance Hodgkin's disease: the use of bcl-6 and CD57 in diagnosis and differential diagnosis. Am J Surg Pathol 2000;24:1068-78.

2Diagnostic Immunohistochemistry edited by Professor D. J. Dabbs, page 70

3Leong A S-Y, Cooper K and Leong FJ W-M. Manual of diagnostic antibodies for immunohistology. 2nd edition, 2003

This page last revised 21.12.2001.

©SMUHT/PW Bishop