Nodular pleural plaque

Pleural plaques are non-neoplastic, but may form nodules, mimicking pleural neoplasms. Pleural plaques are strongly associated with asbestos exposure. They are commonly multiple and bilateral. They are composed of hypocellular collagen forming a basket-weave pattern. There may be calcification or osseous metaplasia.

Differential diagnoses

• Desmoplastic mesothelioma

• Other spindle cell pleural neoplasms

References

¹ Granville L, Laga AC, Allen TC, et al. Review and update of uncommon primary pleural tumors: a practical approach to diagnosis. Arch Pathol Lab Med 2005; 129:1428-43

This page last revised 8.8.2006.

©SMUHT/PW Bishop