Differential of spindle cell tumours of the pleura

 

CD34

bcl-2

CD99

cytokeratin

EMA

calretinin

desmin

SMA

 

SFT

+

+

+

-

-

-

some, focally

rare, focally

 

desmoid tumour

-

 

 

-

-

 

+

+

 

sarcomatoid mesothelioma

-

some

some

+

+

+

some

+

 

synovial sarcoma

-

+

variable

+

+

 

 

 

 

pleural thymoma, WHO type A

-

some

lymphocytes only

+

-

stromal cells only

 

 

 

smooth muscle tumour

some

some

some

 

 

 

+

+

 

haemangiopericytoma

+

 

variable

 

 

 

 -

 

neurofibroma

most

+

 

 

 

 

 

 

 

schwannoma

some

+

 

 

 

 

 

 

 

malignant peripheral nerve sheath tumour

rare

some

 

rare

 

 

  rare

 

   rare

 

 

spindle cell lipoma

+

+

 

 

 

 

 

 

 

calcifying fibrous pseudotumour

variable

   

-

 

-

-