Pulmonary meningioma

Pulmonary meningioma

Epidemiology

This is a very rare tumour, with about 20 cases in the world literature.

Clinical features

Age range is 41 to 75, with a mean of 52 years. The lesions are usually asymptomatic.

Histopathology

The appearances are the same as those of meningioma of the central nervous system.

Immunohistochemistry

vimentin	positive
EMA	positive
Cytokeratins	may be focally positive
S-100	may be focally positive
CD34	may be focally positive
desmin	negative
actin	negative
chromogranin	negative
bombesin	negative
NSE	negative

Differential diagnosis

Metastatic meningioma. Secondary meningioma may have a very long latent period.
Haemangiopericytoma; these lack the psammoma bodies seen in meningiomas.
Neurilemmoma.
Paraganglioma.

Prognosis

Benign

References

Spencer's Pathology of the Lung.

Diagnostic histopathology of tumors. Edited by CDM Fletcher. 2nd edition. Churchill Livingstone. Page 191.

Moran CA, Hochholzer L, Rush W, Koss MN. Primary intrapulmonary meningiomas, a clinicopathological and immunohistochemical study of 10 cases. Cancer 1996;78:2328-33.