Insular carcinoma of the thyroid (poorly differentiated carcinoma

Immunohistochemistry

cytokeratin	+
thyroglobulin	+ (may be confined to abortive follicles and isolated cells)
calcitonin	-
bcl-2	84%

bcl-2 is more often positive in insular carcinoma than in anaplastic carcinoma.

References

Diagnostic histopathology of tumors. Edited by CDM Fletcher. 2nd edition. Churchill Livingstone. Pages 998.

This page last revised 12.6.2001.