Testicular seminoma

Cam5.2	19/641
AE1/AE3	23/641
WSK	23/641
HMWK	0/641
CK7	26/641
CK20	0/641
EMA	1/641, 0/72
PLAP	64/641, 6/72, 199/199 (strong in 193 and weak in 6 cases)3
CEA	0/72
HCG	0/72
AFP	0/72
vimentin	0/7
CD15	0/72
CD30	4/641, 0/72
NSE	7/72

Differential diagnosis

• Seminoma-like Sertoli cell tumour

References

¹Cheville, J. C., Rao, S., Iczkowski, K. A., Lohse, C. M., Pankratz, V. S. Cytokeratin expression in seminoma of the human testis. Am J Clin Pathol 2000; 13: 583-8.

²Ro J et al. Nonseminomatous germ cell tumors of the testis: an immunohistochemical study of 46 cases. Lab Invest 1991;64:50A.

³Tissue array of a historical archive: the British Testicular Tumour Panel Series. Pathological Society January 2005, abstract 58.

©SMUHT/PW Bishop