Myoepithelioma of salivary gland

Immunohistochemistry

	benign myoepithelioma	malignant myoepithelioma
pan-cytokeratin	positive	9/101
Calponin	positive	10/101
S-100	positive	10/101
GFAP	positive	5/101
muscle actin	positive	7/101
cytokeratin 7	0/72
cytokeratin 8/18	0/172
cytokeratin 14	10/101, 5/72
cytokeratin 19	9/172
EMA	often positive	10/101
CEA	rarely positive	0/101

Ectomesenchymal chondromyxoid tumour of the anterior tongue may be a variant of myoepithelioma and shows the same immunoreactivity.

References

Diagnostic histopathology of tumors. Edited by CDM Fletcher. 2nd edition. Churchill Livingstone. Page 249.

¹Nagao, T et al. Salivary gland malignant myoepithelioma: a clinicopathologic and immunohistochemical study of ten cases. Cancer 1998;83:1292-9.

²Chu, P. G. and L. M. Weiss (2002). "Keratin expression in human tissues and neoplasms." Histopathology 40(5): 403-39. (Summary data from multiple papers)

This page last revised 31.12.2003.

©SMUHT/PW Bishop