Pleomorphic adenoma of salivary gland

Similar tumours may rarely arise from skin adnexa. A very few similar tumours have been reported as occurring in bone¹.

Immunohistochemistry

	glandular cells	myoepithelial cells
EMA	positive	negative
CEA	positive	negative
cytokeratin	positive	positive
cytokeratin 5/6	26/282
cytokeratin 7	9/92
cytokeratin 14	12/122
cytokeratin 19	12/122
cytokeratin 20	0/562
vimentin		positive
actin		variable
myosin		variable
S-100	variable	usually positive
GFAP		usually positive
Calponin		positive

References

¹Kamiymama K et al. Aggressive mixed tumour, salivary gland type of the bone. Histopathology 2003;43:408-410.

²Chu, P. G. and L. M. Weiss (2002). "Keratin expression in human tissues and neoplasms." Histopathology 40(5): 403-39. (Summary data from multiple papers)

This page last revised 31.12.2003.