Acinic cell tumour of salivary gland

Similar tumours rarely occur in the breast3.

Immunohistochemistry

cytokeratins

positive1

AE1/AE3

11/114

cytokeratin 7

28/282, 17/114

cytokeratin 13

0/82

cytokeratin 14

0/82

cytokeratin 19

0/82

cytokeratin 20

0/114

CEA

positive1

amylase

15%1

References

1 Diagnostic histopathology of tumors. Edited by CDM Fletcher. 2nd edition. Churchill Livingstone. Page 273.

2 Chu, P. G. and L. M. Weiss (2002). "Keratin expression in human tissues and neoplasms." Histopathology 40(5): 403-39. (Summary data from multiple papers)

3 Coyne, J. D. and P. A. Dervan (2002). "Primary acinic cell carcinoma of the breast." J Clin Pathol 55(7): 545-7.

4 Meer S,Altini M. CK7+/CK20- immunoexpression profile is typical of salivary gland neoplasia. Histopathology 2007; 51:26-32

This page last revised 4.8.2007.

©SMUHT/PW Bishop