Paediatric adrenal cortical neoplasms are rare, most being carcinomas.
In contrast to adults, paediatric tumours are often hormonally active: children often present with virilisation or Cushing's syndrome, rarely with feminisation or Conn's syndrome. Congenital syndromes associated with paediatric adrenocortical neoplasms include hemihypertrophy, urinary tract abnormalities, adrenal cytomegaly, Beckwith-Wiedemann syndrome, Li-Fraumeni and SBLA.
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100%1 |
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84%1 |
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72%1 |
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27%1 |
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|
10%1 |
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|
13%1 |
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|
10%1 |
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0%1 |
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17%1 |
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|
30%1 |
|||
|
4%1 |
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|
0%1 |
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|
3%1 |
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|
3%1 |
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|
8%1 |
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|
0%1 |
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|
37%1 |
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|
50%1 |
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The strong positivity for inhibin may be diagnostically useful.
vena cava invasion
Other predictors on univariate analysis1:
tumour weight > 400g
This page last revised 14.1.2004.
©SMUHT/PW Bishop