Paediatric adrenal cortical neoplasms are rare, most being carcinomas.
In contrast to adults, paediatric tumours are often hormonally active: children often present with virilisation or Cushing's syndrome, rarely with feminisation or Conn's syndrome. Congenital syndromes associated with paediatric adrenocortical neoplasms include hemihypertrophy, urinary tract abnormalities, adrenal cytomegaly, Beckwith-Wiedemann syndrome, Li-Fraumeni and SBLA.
100%1 |
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84%1 |
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72%1 |
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27%1 |
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10%1 |
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13%1 |
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10%1 |
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0%1 |
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17%1 |
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30%1 |
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4%1 |
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0%1 |
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3%1 |
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3%1 |
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8%1 |
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0%1 |
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37%1 |
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50%1 |
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The strong positivity for inhibin may be diagnostically useful.
vena cava invasion
Other predictors on univariate analysis1:
tumour weight > 400g
This page last revised 14.1.2004.
©SMUHT/PW Bishop