Seminal vesicle adenocarcinoma

n

Ca-125

CK7

CK20

prostate specific antigen

prostatic acid phosphatase

4

3

3

0

-

-

References

"In conclusion, the present study has shown that the CK7- positive, CK20-negative, CA-125-positive, PSA/PAP-negative immunophenotype of papillary SVCA is unique and can be used in conjunction with histomorphology to distinguish it from other tumors that enter the differential diagnosis, including prostatic adenocarcinoma (CA-125 negative, PSA/PAP positive), bladder transitional cell carcinoma (CK20 positive, CA-125 negative), rectal adenocarcinoma (CA-125 negative, CK7 negative, CK20 positive), bladder adenocarcinoma (CA-125 negative), and adenocarcinoma arising in a Mullerian duct cyst (CA-125 negative)."1

1Ormsby A.H., Haskell, R., Jones, D., Goldblum, J. R. Primary seminal vesicle carcinoma: an immunohistochemical analysis of four cases. Mod Pathol 2000;13:46-51.

 

©SMUHT/PW Bishop