Comparison of sensitivities and specificities of T and B cell markers
|
percentages of cases showing immunoreactivity |
(NCL-CD3-PS1) |
|||||
|
Low grade B-cell NHL |
81% (22/27) |
85% (23/27) |
26% (7/27) |
4% (1/24 |
4% (1/27) |
0% (0/27) |
|
High grade B-cell NHL |
100% (18/18) |
67% (12/18) |
17% (3/18) |
6% (1/17) |
0% (0/18) |
0% (0/18) |
|
Low grade T-cell NHL |
0% (0/9) |
0% (0/9) |
100% (11/11) |
90% (26/29) |
100% (11/11) |
100% (11/11) |
|
High grade T-cell NHL |
0% (0/21) |
0% (0/21) |
95% (20/21) |
95% (19/20) |
57% (12/21) |
48% (10/21) |
References
M Steward et al. Production and characterization of a new monoclonal antibody effective in recognizing the CD3 T-cell associated antigen in formalin-fixed embedded tissue. Histopathology 1997;30:16-22.
©SMUHT/PW Bishop