Home > Tumours > Genitourinary tract > Bladder > Urothelial carcinoma, S100P & GATA3
Reference 1 |
Polyclonal anti-S100P, S0084 % positive (number of cases studied), nuclear with or without cytoplasmic |
monoclonal S100P % positive (number of cases studied), nuclear with or without cytoplasmic |
% positive (number of cases studied) |
||
Renal urothelial |
94% of 17 |
80% of 15 |
67% of 15 |
||
Bladder urothelial, high grade |
81% of 215 |
71% of 219 |
57% of 226 |
||
Bladder urothelial, low grade |
100% of 80 |
96% of 81 |
95% of 82 |
||
Bladder urothelial, all |
67% of 308 |
||||
Bladder, squamous cell |
0 of 7 |
0 of 7 |
0 of 7 |
||
Stomach |
58% of 19 |
62% of 21 |
0 of 15 |
||
Oesophageal adenocarcinoma |
4 of 4 |
3 of 5 |
0 of 4 |
||
Oesophageal squamous |
0 of 7 |
0 of 8 |
0 of 8 |
||
Pancreatic |
4 of 6 |
3 of 10 |
0 of 6 |
||
Colorectal |
61% of 72 |
20% of 80 |
0 of 71 |
||
Hepatocellular |
36% of 11 |
14% of 14 |
0 of 13 |
||
Lung |
27% of 41 |
10% of 48 |
0 of 45 |
||
Ovary |
15% of 40 |
7% of 41 |
0 of 39 |
||
Prostate |
3% of 260 |
2% of 256 |
0 of 257 |
||
Adrenal |
0 of 3 |
0 of 3 |
0 of 3 |
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Breast ductal |
1 of 4 |
0 of 4 |
4 of 4 |
||
Cervical adenocarcinoma |
1 of 4 |
0 of 5 |
0 of 4 |
||
Cervical squamous |
2 of 4 |
0 of 6 |
0 of 6 |
||
Endometrial |
7% of 30 |
0 of 31 |
0 of 27 |
||
Gallbladder |
0 of 1 |
0 of 1 |
0 of 1 |
||
Melanoma |
0 of 13 |
0 of 16 |
0 of 12 |
||
Renal clear cell |
1% of 125 |
0 of 125 |
0 of 111 |
||
Renal papillary |
0 of 9 |
0 of 9 |
0 of 9 |
||
Renal chromophobe |
0 of 12 |
0 of 12 |
0 of 11 |
||
Renal sarcomatoid |
0 of 2 |
0 of 2 |
0 of 2 |
||
Seminoma |
0 of 10 |
0 of 10 |
0 of 6 |
||
Squamous NOS |
19% of 16 |
0 of 20 |
0 of 23 |
||
Thyroid |
0 of 14 |
0 of 17 |
0 of 18 |
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The monoclonal antibody has greater specificity for urothelial neoplasms, at the expense of lower sensitivity1.
p63 and CK5/6 were studied on the same cases:
|
p63 |
CK5/6 |
||
urothelial carcinoma |
||||
renal cell carcinoma |
0 of 117 cases |
7 of 131 cases |
||
prostatic carcinoma |
1 of 251 cases |
11 of 254 |
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References
This page last revised 30.5.2007.
©SMUHT/PW Bishop