Home > Sarcomatoid mesothelioma
Sarcomatoid mesothelioma is now more of a challenge than epithelioid or biphasic mesothlioma. Markers that have a high sensitivity for epithlioid mesotherlioma tend to have far lower sensitivity in sarcomatoid mesothelioma. Diagnosis of sarcomatoid mesothelioma is largely one of exclusion9.
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Mesothelioma |
epithelioid |
16/221, 16/162 |
0/121 |
4/51 |
4/121 |
11/162 |
13/162 |
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8/162 |
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biphasic |
0/11 |
0/11 |
0/11 |
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epithelioid component of biphasic |
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9/102 |
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4/102 |
6/102 |
9/102 |
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2/102 |
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sarcomatoid component of biphasic |
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6/102 |
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1/102 |
2/102 |
5/102 |
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6/102 |
9/102 |
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sarcomatoid |
0/81 |
0/41 |
7/81 |
0/102, 9/313, 1/76, 1/87 |
1/102, 0/46, 4/84, 1/87 |
0/76, 3/84 |
6/102 |
7/102, 24/313 |
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2/801 |
0/801 |
3/801 |
61/801 |
77/801 |
4/801 |
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1/131 |
1/151 |
0/161, 6/102, 0/43 |
0/161 |
6/161 |
9/161 |
0/102, 0/43 |
0/102 |
4/102, 0/43 |
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1/102 |
9/102, 4/43 |
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Sarcomas |
1/81 |
0/81 |
0/71 |
3/71 |
6/71 |
1/242 |
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Sarcomatoid carcinoma
of lung
of kidney: both sarcomatoid mesothelioma and sarcomatoid renal cell carcinoma may be posiitve for CD10 and renal cell carcinoma antigen7.
Spindle cell malignant melanoma
Sarcoma
monophasic synovial sarcoma: positive for cytokeratins including CK5/6, and calretinin
angiosarcoma
leiomyosarcoma
malignant solitary fibrous tumour
Spindle cell thymoma: positive for cytokeratins including CK5/6, and calretinin
©SMUHT/PW Bishop